Henipaviruses, Hendra virus (HeV) le Nipah virus (NiV) li tsejoa ka ho baka mafu a bolaeang bathong. Ka 2022, Langya henipavirus (LayV), e leng novel henipavirus e ile ea fumanoa ho China Bochabela ho bakuli ba febrile ba tsejoang nalane ya moraorao ya ho iphumana le diphoofolo. Phuputsong ea morao tjena, bafuputsi ba tlaleha ho sibolloa ha pele ha li-henipaviruses tse peli tse tsoang liphiong tsa bo-'mankhane ba lulang serapeng sa lifate tsa litholoana haufi le metsana e profinseng ea Yunnan ea China. Likokoana-hloko tse peli tse sa tsoa hlaha ke mefuta e fapaneng ea phylogenetically 'me li amana haufi-ufi le likokoana-hloko tse bolaeang tsa Hendra le Nipah. Sena se hlahisa matshwenyeho mabapi le kotsi e ka bang teng ya spillover kaha bo-mankgagane ba ditholwana (Pteropus) ke dikokwana-hloko tsa tlhaho tse fetisetswang ho batho le mehlape ka dijo tse nang le moroto kapa mathe.
Kokoana-hloko ea Hendra (HeV) le kokoana-hloko ea Nipah (NiV) ea mofuta oa Henipavirus ea lelapa la likokoana-hloko tsa Paramyxoviridae li kotsi haholo. Genome ea bona e na le RNA e nang le moalo o le mong e pota-potiloeng ke enfelopo ea lipid. Ka bobeli li hlahile nakong e fetileng. Kokoana-hloko ea Hendra (HeV) e ile ea tsejoa ka lekhetlo la pele ka 1994-95 ka ho qhoma ha teropo ea Hendra e Brisbane, Australia ha lipere tse ngata le barupeli ba tsona ba tšoaetsoa 'me ba inehela ho lefu la matšoafo ka maemo a tsoang mali. Kokoana-hloko ea Nipah (NiV) e qalile ho tsejoa lilemo tse 'maloa hamorao ka 1998 Nipah, Malaysia ka mor'a ho qhoma ha lehae. Ho tloha ka nako eo, ho bile le linyeoe tse 'maloa tsa NiV lefatšeng ka bophara linaheng tse fapaneng haholo-holo Malaysia, Bangladesh le India. Hangata mafu ana a ne a amahanngoa le lefu le phahameng har'a batho le liphoofolo. Bommamathwane ba ditholwana (Pteropus species) ke dibata tsa bona tsa tlhaho tsa diphoofolo. Tšoaetso e hlaha ho bo-'mankhane ka mathe, moroto le mantle ho ea bathong. Likolobe ke tse amohelang Nipah ha lipere e le tse amohelang HeV le NiV.
Ho batho, tšoaetso ea HeV e hlahisa matšoao a kang a ntaramane pele e fetela ho lefu la encephalitis ha mafu a NiV a atisa ho hlaha e le mafu a methapo ea pelo le encephalitis e matla, 'me maemong a mang, lefu la ho hema. Phetiso ea motho ho ea ho motho e etsahala qetellong ea tšoaetso.
Likokoana-hloko tsa Henipa ke likokoana-hloko tse hlahang ka potlako tsa zoonotic. Ka Phuptjane 2022, kokoana-hloko ea Angavokely (AngV) e ile ea fumanoa lisampong tsa moroto ho tsoa ho bo-'mankhane ba hlaha ba Madagascar. Ka mor'a moo, Langya henipavirus (LayV) e ile ea fumanoa ho tloha 'metsong oa bakuli ba febrile nakong ea tlhahlobo ea balebeli Chaena Phato 2022.
Phuputsong e phatlalalitsoeng ka la 24 Phuptjane 2025, bafuputsi ba fumane likokoana-hloko tse peli tse ncha tsa henipavirus, tse amanang le bo-'mankhane 'me li na le kamano e haufi ea ho iphetola ha lintho le kokoana e bolaeang ea Hendra (HeV) le Nipah virus (NiV). Kaha bo-'mankhane ke mehloli ea tlhaho ea mefuta e mengata ea likokoana-hloko 'me liphio li ka ba le mefuta e mengata ea likokoana-hloko, bafuputsi thutong ena, ho fapana le liphuputso tse ngata tse fetileng tse shebaneng le lisampole tsa mantle, ba hlahlobile lisampole tsa liphio bakeng sa livaerase, libaktheria le likokoana-hloko tse ling. Ho ile ha hlahlobjoa lisele tsa liphio ho tsoa ho bo-'mankhane ba 142 ba mefuta e leshome ea bo-'mankhane ho tsoa libakeng tse hlano profinseng ea Yunnan ea China. Patlisiso ea ts'oaetso eohle ea liphio tsa bat e senotse boteng ba likokoana-hloko tse 'maloa tse kenyelletsang livaerase tse 20 tse ncha. Tse peli tsa livaerase tse ncha e ne e le tsa mofuta oa henipaviruses 'me li ne li amana haufi-ufi le likokoana-hloko tse bolaeang tsa Hendra le Nipah. Mehlala ea liphio e nang le likokoana-hloko tsena tse peli tse ncha tsa henipa e ne e le tsa bo-'mankhane ba lulang serapeng sa lifate tse haufi le metse. Sena se hlahisa matshwenyeho mabapi le kotsi e ka bang teng ya spillover kaha bo-mankgagane ba ditholwana (Pteropus) ke dikokwana-hloko tsa tlhaho tse fetisetswang ho batho le mehlape ka dijo tse nang le moroto kapa mathe.
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References:
- Kuang G., et al 2025. Tlhahlobo ea tšoaetso ea liphio tsa bat ho tloha profinseng ea Yunnan, Chaena, e senola li-henipaviruses tse ncha tse amanang le likokoana-hloko tsa Hendra le Nipah le likokoana-hloko tse atileng tsa baktheria le eukaryotic. PLOS Pathogen. E phatlalalitsoe: 24 June 2025. DOI: https://doi.org/10.1371/journal.ppat.1013235
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Lihlooho tse amanang:
- Kokoana-hloko ea Novel Langya (LayV) e fumanoe Chaena (10 August 2022)
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 and Nipah virus (NiV) are known to cause fatal diseases in humans. In 2022, Langya henipavirus (LayV), a novel henipavirus was identified in Eastern China in febrile patients with known recent history of exposure to animals. In a recent study, researchers report the first detection of two novel henipaviruses from kidneys of bats inhabiting orchard near villages in Yunnan province of China. The two newly emerged henipaviruses are phylogenetically distinct strains and are closely related to lethal Hendra and Nipah viruses. This raises concern about potential spillover risk since fruit bats (Pteropus) are natural hosts of henipaviruses which are usually transmitted to humans and livestock through food contaminated with bat urine or saliva.){kind=link}